Publications
Selected Publications
Spencer, S.L., Gaudet, S. Albeck, S.G. Burke, J.M. & Peter K.
Sorger (2009) Non-genetic origins of cell-to-cell variability in
TRAIL-induced apoptosis, Nature. 2009 May 21;459(7245):428-32. Epub 2009 Apr 12.
PMID: 19363473. doi:10.1038/nature08012
Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB,
Lauffenburger DA, Sorger PK. (2009) Input-output behavior of ErbB
signaling pathways as revealed by a mass action model trained against
dynamic data. Mol Syst Biol. 2009;5:239. Epub 2009 Jan 20.
PMID: 19156131. doi: 10.1038/msb.2008.74
Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger
PK. (2008) Quantitative analysis of pathways controlling extrinsic
apoptosis in single cells. Mol Cell 30(1): 11-25. Download PDF
Fitzgerald JB, Schoeberl B, Nielsen UB, Sorger PK. (2006) Systems
biology and combination therapy in the quest for clinical efficacy.
Nat Chem Biol 2(9): 458-66. Download PDF
Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger
PK. (2006) The response of human epithelial cells to TNF involves an
inducible autocrine cascade. Cell 124(6): 1225-39. Download PDF
Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK. (2000)
Chromosome missegregation and apoptosis in mice lacking the mitotic
checkpoint protein Mad2. Cell 101(6): 635-45. Download PDF
Kaplan KB, Hyman AA, Sorger PK. (1997) Regulating the yeast
kinetochore by ubiquitin-dependent degradation and Skp1p-mediated
phosphorylation. Cell 91(4): 491-500. Download PDF
Sorger PK, Murray AW. (1992) S-phase feedback control in budding
yeast independent of tyrosine phosphorylation of p34cdc28. Nature
355(6358): 365-8. Download PDF
Sorger PK. (1990) Yeast heat shock factor contains separable
transient and sustained response transcriptional activators. Cell
62(4): 793-805. Download PDF
Sorger PK, Lewis MJ, Pelham HR. (1987) Heat shock factor is
regulated differently in yeast and HeLa cells. Nature 329(6134): 81-4. Download PDF
